Incredible performance for all ages


Colostrum is our first food of life, and we get it from our mother’s breast immediately after birth. A mother’s colostrum is rich in immunoglobulins which provides immunity to the hostile, germ-filled world in which mammals are born. Of note, immunoglobulins from colostrum were used by Dr. Jonas Salk to develop the first oral polio vaccine[1]. John Heinerman, PhD, one of the world’s leading medical anthropologists and the author of more than 50 books on health and nutrition, stated that without colostrum, humans would be extinct[2].

Colostrum is one of nature's most powerful foods, a “superfood” by today’s definition. As the first food of life, colostrum helps an infant ward off and fight infection[3]. It helps stimulate epithelium cell growth in the intestines to close stomach and intestinal openings that are naturally present at birth. Once colostrum’s bioactive components have entered the bloodstream, they provide the building blocks of a new immune system; this is Mother Nature’s way of creating perfect health[4]. Colostrum readies the body for nutrition (mother’s milk) and helps populate the bowel with healthy bacteria and enhances their growth and colonization[5]

Mother’s colostrum activates and stimulates immune responses to pathogens, including viruses[6],[7],[8], bacteria[9], protozoa, and fungus[10],[11] in the newborn. Colostrum also activates the creation and accelerates function of the immune response, including macrophages, T-cells, and natural killer (NK) cells (which destroy infected or diseased cells in our body, making them up to 20 times more effective)[12]

Colostrum’s cytokines help reduce inflammatory response and the pain of birth, and they provide signals that calm and soothe the newborn via the activation of serotonin[13] (a neurotransmitter produced in the gut and utilized in the brain). Colostrum also helps balance blood glucose levels[14]in the body.


Colostrum is bio-compatible in its form, composition, and function. But only colostrum collected from healthy sources, typically cows or goats, which has been gently processed with the utmost care and protected from degradation is valuable as a nutritional supplement.

Colostrum helps support:

  • Immune System: Colostrum is the only immune support that does not rev up an overactive immune response[15]. Colostrum’s bioactive components help balance immune responses and can assist in bringing back into balance overactive or improper immune responses that are associated with autoimmune conditions[16], allergies[17], asthma, diabetes[18], etc. Colostrum is the only immune support appropriate for these conditions[19]
  • Athletes: Clinical studies show colostrum may help athletes have up to 20% more lean muscle strength[20], stamina, and performance[21],[22], strengthen immune defenses (helps eliminate post-workout susceptibility to infections)[23], and accelerate healing from injuries and strenuous physical exertion[24],[25]. Colostrum also helps enhance brain chemical response[26],[27],[28].
  • Blood Pressure: Milk has long been known for its ability to help people maintain healthy blood pressure[29]. Peptides have been identified in milk and colostrum that function as ACE-inhibitors to help lower blood pressure.
  • Anti-aging: Colostrum helps reduce inflammation[30],[31] and it may be more effective than antioxidants, growth hormone, or any other therapy for strength, mobility, brain chemical function and protection, and infection defense necessary for active senior lifestyles [32],[33],[34].
  • GI and Stomach Health: Gastrointestinal (GI) permeability (leaky gut) is a pandemic problem that affects a majority of the population[35]. Leaky gut is acknowledged to be a primary cause of autoimmune and allergic responses and the cause of many chronic diseases[36]. It is caused by taking antibiotics, pain killers and other medications (see FDA warnings), acidic beverages (sodas, coffee etc), alcohol, GMO foods, pesticides, and various environmental factors. It occurs when foreign particles and toxins cross into the bloodstream through the GI and stomach lining, resulting in adverse immune reactions, internal infections, and other medical conditions. Some scientists believe that a majority of infectious and chronic diseases begin in the GI tract, and colostrum helps prevent and heal GI damage. In fact, colostrum's growth factors have been shown to help prevent and heal stomach and GI damage[4], [37], [38].

Why Colostrum-LD® (Liposomal Delivery)?

Colostrum has large and small molecules that are sensitive to light and heat. When colostrum is fresh from the mother, colostrum's small molecules are absorbed in the mouth and throat and are quickly distributed throughout the body to initiate immediate immune response and communication. Then, colostrum's large molecules travel on to the small intestine where they cross through the bowel wall and into the bloodstream.

Colostrum-LD® is obtained from pasture-raised, U.S.-grade A dairy cows that have been certified healthy and mad cow-free; they are also not supplemented with rBST (a synthetic growth hormone) nor are they regularly fed antibiotics. Once the baby calf has had its fill of its mother’s colostrum, the remaining is harvested and gently processed.Then, Colostrum-LD® is encapsulated into a liposome (structural coating) comprised of phosphatidylcholine, phosphatidylserine, and other phospholipids from milk and sunflower that protect and enhance the delivery of all of colostrum's bioactive components to the body's intestines, organs, and cellular structures. Liposomal delivery (LD) which is proprietary to Colostrum-LD®, is a state-of-the-art delivery system that has decades of science behind it. LD allows Sovereign Laboratories to guarantee the performance and effectiveness of Colostrum-LD®.

Robert D. Milne, MD certifies in his book on liposomal encapsulation that: “Liposomal encapsulation has a proven ability to enhance usability and bioavailability by up to 1,500% or more”[39]

Colostrum-LD® is certified to contain a minimum of 25-30% immunoglobulins, 1.5% lactoferrin, 1.5% growth factors, and 3.5-5% CPs. It is also standardized, cGMP-, Halal-, Kosher-certified, and manufactured in a USDA-licensed facility. The lactase enzyme has been added to reduce lactose content and make Colostrum-LD® suitable for lactose-free diets.

Colostrum’s small components are called peptides (proteins). The most significant peptides include proline-rich polypeptides (PRPs)-- which have been renamed colostrum polypeptides (CPs) by some -- cytokines, interleukins, interferon, and other immune factors. These components are susceptible to degradation by stomach acids and digestive enzymes. Thus, Sovereign Laboratories has found a method by which these immune components can be extracted, concentrated, and delivered in an oral spray. This patent-pending process allows Sovereign Laboratories to create immune health sprays which are easy to administer, especially for children.

It Doesn’t Get Any Better Than Colostrum-LD®

Douglas Wyatt is considered one of the world’s leading experts on bovine colostrum. He was the founder of Symbiotics (now owned by a natural foods conglomerate). He later founded Sovereign Laboratories to expand the development and delivery to the public of the finest and most-effective colostrum products in the world.

For more than 25 years, Douglas Wyatt has dedicated his life’s work to the prevention of chronic disease and infection. He discovered colostrum through the efforts to save his wife, Kaye, whose non-functioning immune system (the result of medical treatment in childhood) left her susceptible to chronic infections. He serves as research director of the Center for Nutritional Research, which is dedicated to colostrum research and its relation to human health and longevity. Over the decades, Mr. Wyatt sponsored numerous clinical studies with colostrum and advised researchers on clinical work related to GI health, infant health, autism, HIV, flu, athletic response, and hospital-associated infections. Douglas Wyatt’s passion is helping others achieve health independence, freedom, and vitality. His hope is that every individual can and will take charge of their own health through education and personal choices -- health sovereignty. 

Learn more about Sovereign Laboratories and colostrum research at

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, prevent, or cure any disease.

© This document in its entirety is copy protected by Sovereign Laboratories, LLC. Copy or reproduction of any or this entire document is by permission only.


[1] Sabin AB. Antipoliomyelitic substance in milk from human beings and certain cows.Journal of Diseases of Children 80:866 (1950). PMID: 14777169

[2] Heinerman J. Fascinating Colostrum: An Ancient Food for Modern Times. (1999)

[3] Stelwagen K, Carpenter E, Haigh B, Hodgkinson A, Wheeler TT. Immune Components of Bovine Colostrum and Milk.Journal of Animal Science 87(13 Suppl):3-9 (2008).  PMID: 1892725

[4] Playford RJ, Macdonald CE, Johnson WS. Colostrum and Milk-Derived Peptide Growth Factors for the Treatment of Gastrointestinal Disorders.American Journal of Clinical Nutrition 72(1):5-14 (2000). PMID: 10871554

[5] Gopal PK, Gill HS. Oligosaccharides and glycoconjugates in bovine milk and colostrum.British Journal of Nutrition 84 (Suppl 1): S69-S74 (2000). PMID: 11242449

[6] Brüssow H, Hilpert H, Walther I, Sidoti J, Mietens C, Bachmann P. Bovine milk immunoglobulins for passive immunity to infantile rotavirus gastroenteritis.Journal of Clinical Microbiology 25(6):982-986 (1987). PMID: 3036910

[7] Harmsen MC, Swart PJ, de Bethune MP, Pauwels R, De Clercq E, The TH, Meijer DK. Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro.Journal of Infectious Diseases172(2):380-388 (1995). PMID: 7622881

[8] Superti F, Ammendolia MG, Valenti P, Seganti L. Antirotaviral activity of milk proteins: lactoferrin prevents rotavirus infection in the enterocyte-like cell line HT-29.Medical Microbiology and Immunology (Berlin) 186(2-3):83-91 (1997).  PMID: 9403835

[9] Ellison RT III, Giehl TJ. Killing of gram-negative bacteria by lactoferrin and lysozyme.Journal of Clinical Investigation 88(4):1080-1091 (1991). PMID: 1918365

[10] van Hooijdonk, AC, Kussendrager, KD, Steijns, JM. In vivo antimicrobial and antiviral activity of components in bovine milk and colostrum involved in non-specific defense. British Journal of Nutrition 84(Suppl.1):S127-S134 (2000). PMID: 11242457

[11] Andersson Y, Lindquist S, Lagerqvist C, Hernell O. Lactoferrin is responsible for the fungistatic effect of human milk.Early Human Development 59:95-105 (2000). PMID: 10996747


[13] Markus CR, et al. The bovine protein alpha-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress. American Journal of Clinical Nutrition 71(6):1536-1544 (2000). PMID: 10837296

[14] Dohm GL, Elton CW, Raju MS, Mooney ND, DiMarchi R, Pories WJ, Flickinger EG, Atkinson SM Jr, Caro JF. IGF-I– Stimulated Glucose Transport in Human Skeletal Muscle and IGF-I Resistance in Obesity and NIDDM.Diabetes 39(9):1028-1032 (1990). PMID: 2166697

[15] Zimecki M. A proline-rich polypeptide from bovine colostrum: colostrinin with immunomodulatory activity.Advances in Experimental Medicine and Biology 606:241-250 (2008). PMID: 18183932

[16] Dutta RC. Peptide immunomodulators versus infection; an analysis. Immunology Letters. 83(3):153-61 (2002). PMID: 12095755

[17] Kruzel M, Bacsi A, Choudhury B, Sur S, Boldogh I. Lactoferrin decreases pollen antigen-induced allergic airway inflammation in a murine model of asthma. Immunology 119(2):159-66 (2006). PMID: 16800860

[18] Kim JH, et al. Health-promoting effects of bovine colostrum in Type 2 diabetic patients can reduce blood glucose, cholesterol, triglyceride and ketones.Journal of Nutritional Biochemistry 20(4):298-303 (2009). PMID: 18602824

[19] Zimecki M, Artym J. [Therapeutic properties of proteins and peptides from colostrum and milk]Postȩpy Higieny i Medycyny Doświadczalnej 59:309-323 (2005). PMID:

[20] Antonio J, Sanders MS, Van Gammeren D. The effects of bovine colostrum supplementation on body composition and exercise performance in active men and women.Nutrition 17(3):243-247 (2001). PMID: 11312068

[21] Coombes JS, Conacher M, Austen SK, Marshall PA. Dose effects of oral bovine colostrum on physical work capacity in cyclists.Medicine and Science in Sports and Exercise 34(7):1184-1188 (2002). PMID: 12131260

[22] Hofman Z, Smeets R, Verlaan G, Lugt R, Verstappen PA. The effect of bovine colostrum supplementation on exercise performance in elite field hockey players. International Journal of Sports Nutrition and Exercise Metabolism 12(4):461-469 (2002). PMID: 12500989

[23] Brinkworth GD, Buckley JD. Concentrated bovine colostrum protein supplementation reduces the incidence of self-reported symptoms of upper respiratory tract infection in adult males. European Journal of Nutrition 42(4):228-232 (2003). PMID: 12923655

[24] Kasemkijwattana C, Menetrey J, Bosch P, Somogyi G, Moreland MS, Fu FH, Buranapanitkit B, Watkins SS, Huard J. Use of growth factors to improve muscle healing after strain injury. Clinical Orthopedics 370:272-285 (2000). PMID: 10660723

[25] Molloy T, Wang Y, Murrell G. The roles of growth factors in tendon and ligament healing.Sports Medicine 33(5):381-394 (2003). PMID: 12696985

[26] Kidd PM. Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management. Alternative Medicine Review 5(5):402-428 (2000). PMID: 11056411

[27] Meisel H, FitzGerald RJ. Opioid peptides encrypted in intact milk protein sequences. British Journal of Nutrition 84(Suppl 1):S27-S31 (2000). PMID: 11242443

[28] Miclo L, et al. Characterization of alpha-casozepine, a tryptic peptide from bovine alpha(s1)-casein with benzodiazepine-like activity.FASEB Journal 15(10):1780-1782 (2001). PMID: 11481228

[29] FitzGerald RJ, Meisel H. Lactokinins: whey protein-derived ACE inhibitory peptides.Nahrung 43(3):165-167 (1999). PMID: 10399349

[30] Goldman AS, Goldblum RM, Hanson LA. Anti-inflammatory systems in human milk.Advances in Experimental and Medical Biology 262: 69-76 (1990). PMID: 2181825

[31] Britigan BE, Serody JS, Cohen MS. The role of lactoferrin as an anti-inflammatory molecule.Advances in Experimental and Medical Biology357:143-156 (1994).  PMID: 7762426

[32] Borissenko M. Glutathione: A powerful anti-oxidant found in colostrum. NZMP August 2002.

[33] Lomaestro BM, Malone M. Glutathione in health and disease: pharmacotherapeutic issues.Annals of Pharmacotherapy 29(12):1263-1273 (1995). PMID: 8672832

[34] Buescher ES, McIlheran SM. Antioxidant properties of human colostrum. Pediatric Research 24(1):14-19 (1988). PMID: 2842722

[35] Marston,W. Gut reactions.Newsweek Nov. 17, 1997:95-99.

[36] Hollander D. Intestinal permeability, leaky gut, and intestinal disorders. Current Gastroenterology Reports 1(5):410-416 (1999). PMID: 10980980

[37] Playford RJ, Floyd DN, Macdonald CE, Calnan DP, Adenekan RO, Johnson W, Goodlad RA, Marchbank T. Bovine colostrum is a health food supplement which prevents NSAID induced gut damage. Gut. 1999;44:653-658.

[38] Playford RJ, MacDonald CE, Calnan DP, Floyd DN, Podas T, Johnson W, Wicks AC, Bashir O, Marchbank T. Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability. Clinical Science (London). 2001 Jun;100(6):627-33."

[39]Milne RD. Lipsosomal Encapsulation Technology, Life’s Fountain Books, 2004.