Bovine Colostrum: The Only Natural Source of IGF-l and TGF Nature's Most Powerful Anti-Aging Substances
A Finnish study shows elevated levels of IGF-1 in blood serum after oral administration of colostrum
By Donald R. Henderson, MD, MPH
The New England Journal of Medicine reported that the most effective means to stop or slow the aging process would be to replace the hormonal factors that cause the human body to grow normal cellular structures. After maturity (between the ages of 16-20), the level of growth hormone that the body naturally produces dwindles. As a result, the body loses muscle tone and skin elasticity, causing sagging and wrinkling. The body also shrinks and loses bone mass, while the hands, feet, nose and ears get larger.
Colostrum's perfectly balanced combination of immune and growth factors, administered in human clinical trials with aged subjects, safely increases IGF-1 to pre-puberty levels, producing increased muscle weight and strength. Also, in a double-blind study with members of the Finnish Olympic ski team, subjects displayed elevated levels of IGF-l in blood serum, and significantly increased stamina, performance and recovery time. This agrees with the results of a recent study at the University of South Australia, in which athletes displayed improved stamina and recovery time. The growth factors in colostrum have been shown to tone muscles "melt" body fat, return elasticity to the skin and increase bone density, giving aging adults real hope that there may be a Fountain of Youth after all.
Colostrum supports the human organism in two main ways. First, its multiple immune factors and natural antibiotics provide strong support for the immune system. Second, its many growth factors offer a broad-spectrum boost to encourage optimum health and healing.
Colostrum’s Growth Factors
Colostrum contains many important growth factors, which promote healing and actually create an anti-aging response.
The major factors are "Somatomedin C" (now popularly called IGF-l) IGF-2, and Transforming Growth Factor alpha and beta (TGF A & B). The many regenerative effects of IGF-1, coupled with those of TGF, extend to nearly all structural cells of the body. Without exception, each new published study documents the enhancements of DNA (see below) and protein synthesis as well as nutrient uptake mediated by these colostral growth factors, particularly in muscle and cartilage. These twin healing properties have muscle and cartilage repair characteristics that are biochemically unsurpassed.
Risk Factors of Hormone Replacement Therapy
Isolated hormone replacement therapy has become a popular anti-aging remedy. But most hormonal replacements are synthesized from plant sources and are not identical to the hormones made by the body. These synthesized and isolated hormones can produce life threatening body imbalances and side effects. The main side effects, which include edema, carpal tunnel syndrome and joint aches and pains, are most often caused by overdosing. Some scientists also are concerned that isolated hormone replacement therapy might increase cancer risk by promoting the growth of tumor cells.
Colostrum has no side effects and causes no damage to soft tissues or organs. Yet its effectiveness is documented in many credible studies.
An Australian study shows that stamina and strength in athletes increases up to 20% after consistent use of colostrum.
Colostrum Repairs the Body's Vital DNA and RNA
Everything in life springs forth from DNA - flesh, bones, hormones, nervous system, a baby's first word, the euphoria that comes with first love, and ability to learn to speak a foreign language. This silent intelligence of life, DNA, attracts the chemicals it needs to form new DNA, which is an essential part of cell division DNA is also able to manufacture RNA, which is nearly identical to DNA and participates as its active counterpart. RNA (the active intelligence) is the traveler sent to produce the proteins needed to build and repair the body. Dr. Benjamin Frank's research on youth and aging indicated that RNA is one of the most critical anti-aging factors. His research showed that IGF- (found naturally in colostrum) is one of the only substances known to stimulate the growth and repair of these key nucleic acids, DNA and RNA.
Immune System Boost
As the immune system is depleted, the aging process is accelerated. Colostrum can help reverse this by strengthening the immune system and replacing actual immune factors that the immune system needs to keep us disease free.
Studies show colostrum contains powerful immune and growth factors that work together to restore potent immune function, help regulate an under or overactive immune system, and act as a potent, broad spectrum natural antibiotic and anti-viral agent. Pharmaceutical antibiotics have no effect on viruses.
Colostrum has been shown to help maintain blood glucose levels to serve the brain. Also, IGF- has been shown to cross the blood brain barrier to help with nerve synapses in the brain, enhancing mental acuity and increasing serotonin levels to brighten our moods.
Colostrum is a natural and healthy means of stimulating the brain to release serotonin and dopamine and prolong their re-uptake. Colostrum also activates the release of other chemicals in the brain that affect alertness and concentration.
A Potential Fountain of Youth
Colostrum is unique because it is the only substance that offers the anti-aging hormones in perfect combination the way nature intended (rather than isolating them). Colostrum works naturally to both replace the body's own growth factors and stimulate the endocrine system to keep producing these vital and revitalizing hormones. There is solid evidence that the growth factors and immune-boosting agents act synergistically in colostrum to form a potent anti-aging substance. With the new anti-aging emphasis in health care, colostrum is one of the most exciting reasons to believe in the potential of "Fountain of Youth."
Noda, et al.. Transforming Growth factor Activity in Human Colostrum" Conn Vol. 75 (pg 19-1120), 1984. '
Francis, G.L., e t al. "Insulin-like growth factors 1 (IGF-l) and 2(IGF-2) in bovine colostrum" Biochemical Journal Vol. 251 (pp 95·108), 1988.
Oda, S.; et. al. "Insulin-like growth factor-l (IGF-1), growth hormone (GH). insulin and glucagon concentrations in bovine colostrum and in plasma of dairy cows and neonatal calves around parturition" Compo Bioch£.'YI1. Physiol. Vol 94A (4) (Pl'. 805-808) 1989.
Marcoty et. al. "IgF-l from cow colostrum- characterization; Ig-F potent stimulator of growth and differentiation of numerous cell types" Growth Regulation Longman Group UK, 1991.
Patureau-Mirand, Posone, Levieux, Attaix, et. al., "Effect of Colostrum Feeding on Protein Metabolism in the Small Intestine of Newborn Lambs" Biol . Neonate Vol. 57(1) pp. 30-36) 1990
Shawn, D .• "Colostrum: Bio-technology's Next Step, Ironman. llug. 1992
Rosenthal. Brown Brunetti and Goldfine, "Fibroblast growth Factor Inhibit' Insulin-Like Growth Factor-ll (IGF-ll) Gene Expression and Increases IGF-l Receptor Abundance in BC3H-I Muscle Cells" Dept. of Pediatrics. Univ. of California, SF Div. Of Diabetes and Endocrine Research, Mount Zion Medical Center, Univ, of CA., SF.
Palmer, E. L., et. al.. "Antiviral Activity of Colostrum and Serum Immunoglobulins A and G" Medical Virology, vol. S (pp 123-129), 1980
Rump, J.A.et. at: Treatment of Diarrhea in Human Immunodeficiency Virus-infected patients with Immunoglobulins from Bovine Colostrum” Clinical Investigator Vol 70 (pp588-594) 1992
Wilson, D.C., Ph.D., James "Immune System Breakthrough: Colostrum" Journal of Longevity, Vol. 4 (2), 1998.
Starocik, K; e.t. al., 'Immunologically active non-peptide fragment of a proline-rlch polypeptide (PRP) from bovine colostrum- amino add sequence and immunoregulatory properties" Molecular Immunology, Vol. 20(12) (p1'1277- 1282). 1983.
Moulias R, Belmin J, Lesourd B, Laurent M. Meaume S. Smith .lA, Weidmann MJ, Cuneo RC. Hermine 0, Condamine L, Dupont WD, Rudman D, Rudman IW, Cohn L. Feller A, Lalitha PY, Gergans GA, Nagra HS. Goldberg AF, Mattson DE, Schlenker RA. Vance ML, "Effects of human growth hormone in men over 60 years old' 323 (22); 1561 New England Journal of Medicine, 1990.
Rudman D, Feller AG. Nagraj HS. Gergans GA, Lalitha py. Goldberg AF. Schlenker RA. Cohn L, Rudman rw; Mat.tson DE "Effects of human growth hormone m men over 60 years old' New England Journal of Medici"". ViJlume 323 (1): 1, 1990 Frank Benjamin S., "Doctor Fronk's No-aging Diet' 1981.
Metro A, Mikkulainen H, Pakkanen R, Aalot .T, Takala T. "Effect' of bovine col?strum supplementation on IgF-1, IgG and saliva IgA during training', University of Jyvaskyla, Finland.