Your digestive system is a complex system that is designed to help absorb nutrients, break down food, and expel waste. Stretching about 30 feet from mouth to anus, your alimentary canal is an essential part of the digestive system that supports good health. For instance, your gut plays a key role in fighting off foodborne pathogens by “sterilizing” everything you eat with the active enzymes and acids it secretes. Your gut also is in constant conversation with your immune system via receptors throughout the digestive tract, triggering the release of hormones and other cells that can help to promote general immune functions. One of the key components in your gut is the microbiome, comprising a community of bacteria intended to help fight disease and promote overall health.
Unfortunately, your gut can succumb to a whole host of potential diseases and disorders based on your diet, everyday stress, and a wide range of other factors. Leaky gut syndrome is one of the more common conditions affecting the digestive system. Let’s take a closer look at leaky gut syndrome, the leaky gut diet, and other ways to help you better manage symptoms and maintain good gut health.
What is Leaky Gut Syndrome?
Your intestines are lined with an extensive, intricate lining of tissue that covers over 4,000 square feet of surface area when spread out. Normally in a healthy intestine, this lining forms a tight barrier that manages what gets absorbed into your bloodstream and what gets passed along to the large intestine and excreted as waste.
Leaky gut syndrome, also sometimes known as increased intestinal permeability or intestinal hyperpermeability, is characterized by an unhealthy gut lining that may be full of holes, cracks, or other openings. These fissures allow partially digested food, bacteria, toxins, and other harmful microbes to “leak” into the deeper tissues of your intestine and your bloodstream.
Symptoms of Leaky Gut Syndrome
When the contents of your stomach and intestines leak into the rest of the body, the result is an inflammatory response (inflammation) by the immune system and an alteration in the gut flora. Studies on leaky gut syndrome are still fairly new and constantly expanding, but there’s an understanding that inflammation and changes to your gut’s bacteria can lead to some serious effects in your digestive tract and beyond.
The most common symptoms of leaky gut syndrome include:
- Gas and bloating
- Chronic diarrhea
- Poor immune response (inability to fight infection)
- Nutritional deficiencies
- Headaches and brain fog
- Skin problems, including rashes, eczema, rosacea, or sudden acne
- Joint pain or arthritis
- Depression, anxiety, and other mental disorders
Early research suggests that inflammation and drastic changes to your microbiome can contribute to various chronic and autoimmune diseases.
What Causes Leaky Gut Syndrome?
We understand that leaky gut is caused by increased intestinal permeability, but research is still figuring out how that permeability happens outside of certain types of medications, radiation therapy, and food allergies. Some theorize that the junctions that control what passes through the small intestine’s lining may fail in relation to certain diseases, including celiac disease, Crohn’s disease, and irritable bowel syndrome. This suggests that leaky gut may also be a sign of an underlying problem.
Everyone has a leaky gut to some degree because your intestinal barrier isn’t supposed to be completely impenetrable. If it was, you wouldn’t get the vitamins, minerals, and macronutrients from the food you eat. Some people may be genetically predisposed to a leaky gut or may be more sensitive to sudden changes in the digestive system.
One of the biggest contributors to leaky gut syndrome is the modern Western diet, which tends to be low in fiber and high in sugar and saturated fats. This may trigger increased intestinal permeability. Chronic stress and heavy alcohol use can also disrupt the delicate balance in your gut flora and intestinal lining.
Other potential causes of leaky gut syndrome may include:
- Use of non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen
- Deficiencies in vitamin A, vitamin D, or zinc
- An overgrowth of the yeasts naturally present in your gut
While study and treatment for leaky gut is still early, there are three main tests you can take to determine if you have leaky gut.
The Intestinal Permeability Test
The intestinal permeability test is a urine test that measures how well two non-digestible sugars (mannitol and lactulose) travel through the body and into your intestinal lining. During this test, you drink a solution containing the two sugars and, after six hours, provide a urine sample. The lab then measures the amount of lactulose and mannitol in your urine to determine if you have leaky gut syndrome and to what degree.
The Food Sensitivities Test
The food sensitivities test uses blood or saliva to determine your sensitivity to certain foods. The name of the test and the substance it actually tests for can vary from lab to lab. One test known as the intestinal barrier function test analyzes your blood and saliva to compare the amount of antibodies in your system to the amount of yeast, bacteria, and common allergy-inducing proteins. Another similar test known as the food safe allergy test comprises a comprehensive evaluation of your blood and the presence of antibodies for 95 common foods. All forms of the food sensitivities test are designed to determine the foods that you should avoid, at least until intestinal permeability is returned to acceptable levels.
The Zonulin Test
The zonulin test is a test can be requested in conjunction with a food inflammation test. With the zonulin test, the lab measures the levels of zonulin in your stool or blood to determine the presence of intestinal hyperpermeability. Zonulin is a protein known to open up spaces between cells in your intestinal lining. Increases in zonulin break down the tight junctions between your intestinal cells, which can contribute to cracks, holes, and general permeability.
Zonulin release is mainly triggered by exposure to gluten or harmful bacteria in the small intestine. Zonulin production may increase with exposure to gliadin, a type of protein found in wheat products. Other potential causes of zonulin increase include:
- Candida overgrowth
- Fungal dysbiosis
- Small intestine bacterial overgrowth (SIBO)
The Leaky Gut Diet
The good news is that you can easily manage leaky gut and improve your gut health with some simple changes to your diet.
Remove harmful foods from your diet.
Start by taking away allergens and other foods that may be causing intestinal inflammation, which may include processed grains, refined oils, dairy products, and any foods with added sugar. You should also talk to your doctor about eliminating or replacing any NSAIDs or antibiotics.
Eat foods that will heal your gut.
The leaky gut diet comprises a diverse range of foods that are easy to digest while actively helping to repair your intestinal lining. Some foods you should include in your diet:
- Bone broth – Bone broth is a rich source of collagen, proline, and glycine, all of which can help heal intestinal tissue.
- Fermented vegetables – Along with fiber, fermented vegetables contain acids that can help balance your intestinal pH and gut flora.
- Coconut – Coconut products contain medium-chain fatty acids that are easier to digest while providing you with healthy fats.
- Other healthy fats – Coconut, ghee, avocados, and egg yolk contain healthy fats that are easy to digest and help to promote healing in the gut.
- Sprouted seeds – Sprouted seeds include flax, chia, and hemp and offer excellent sources of fiber, which can help to feed your gut bacteria and support good digestion. However, if you have severe leaky gut symptoms, you may want to start with steamed vegetables and fruit for your fiber.
- Omega-3 fatty acids – Omega-3s are powerful anti-inflammatory compounds that are particularly found in fatty fish, grass-fed beef, lamb, and certain nuts and seeds.
Use supplements to help heal your gut.
Along with foods, dietary supplements can help to heal your gut and rebalance your digestive system. Probiotics are one of the most important supplements because they can help to replenish your gut flora with the beneficial bacteria, which can further help to heal your gut and restore order to your digestive system. Try to get 50 to 100 billion CFUs (colony forming units) of probiotics in your diet per day.
You should also look into supplementing with digestive enzymes. These enzymes can help to ensure that foods get completely digested, which reduces the risk of large food particles and proteins from harming your intestinal lining.
Colostrum is a fluid produced by mammals in the first few days after giving birth before the appearance of true milk. It is packed with a variety of vitamins, minerals, protein, beneficial bacteria, and other nutrients that can help to heal your gut while nourishing your body. Bovine colostrum has been shown in clinical trials to both heal and prevent intestinal hyperpermeability. Its growth factors (hormones) work to restore the integrity of the tight junctions.
Along with a healthy diet, make sure you find a constructive method of dealing with emotional stress. Excess stress can contribute to a leaky gut and harm other components of your health. With the right diet, lifestyle, and daily colostrum supplementation, you can help your G.I. tract and achieve improved health.