Your Gut and Brain Connection May Govern How You Feel

Your Gut and Brain Connection May Govern How You Feel

While research is ongoing, these gut bacteria are believed to help in a variety of ways, such as supporting your immune system. Another avenue of research suggests a unique interplay between your gut and your brain known as the gut-brain axis. Read on to learn more about the gut-brain axis and how you can support this connection for optimal functioning.

Understanding the Gut-Brain Axis

The gut-brain axis refers to a bidirectional connection between the gut and the central and enteric nervous systems. “Bidirectional” means that one can affect the other, and vice versa. It has been long known that depressive disorders are often associated with gastrointestinal issues, while clinical practice often shows a link between dysbiosis and central nervous disorders. Dysbiosis refers to an imbalance in the “good” and “bad” bacteria living within your gut, often resulting in common gastrointestinal issues like diarrhea, constipation, gas, and bloating.

How the Gut-Brain Axis Works

This bidirectional connection between your gut microbiota and your brain is more complex than  G.I. experts currently understand. The actual mode of communication may work by several mechanisms. Research models involving patients who have experienced a stroke or multiple sclerosis have shown that slight changes to the gut bacteria may affect immune homeostasis and immune responses, which may result in an indirect influence on the central nervous system.

Other studies suggest that communication between the gut and the brain is mediated by the vagus nerve, one of the major nerves connecting the gut and brain. Severing the vagus nerve inhibited the anti-anxiety and gene expression effects associated with the bacteria Lactobacillus rhamnosus. Further evidence has shown that stress (in the form of post-traumatic stress disorder, or PTSD) may inhibit activity within the vagus nerve and contribute to gastrointestinal issues.

More recent research has discovered other means of potential communication, particularly the products derived from bacteria within the gut that may signal effects within the nervous system. For instance, offspring from immune-challenged mice exhibited signs of gut dysbiosis, as well as behavioral abnormalities (including anxiety), disrupted intestinal integrity, and high serum levels of a microbial metabolite. Interestingly, when this metabolite was injected into healthy, wild-type mice, it induced anxiety-like behavior.

Neurotransmitters are chemicals produced in the brain that signal various behaviors and control emotions. Many of the neurotransmitters produced in the brain are also coincidentally produced by the gut cells and the gut bacteria. For example, serotonin is the neurotransmitter responsible for contributing to feelings of happiness and well-being, and a deficiency of serotonin is often characteristic of clinical depression. However, a large proportion of the body’s serotonin is housed within the gastrointestinal tract.

How to Support the Gut-Brain Axis

While the exact biological mechanisms of how your gut and brain communicate still require further research, there’s an understanding that supporting your gut bacteria can contribute to a healthy gut-brain axis and better health overall.


Colostrum is produced by female mammals prior to the production of breast milk. It’s a nutrient-dense substance and necessary for newborn mammals to maintain a healthy immune system. Although humans receive most of their immunities from the placenta, mother’s colostrum is vital to optimal growth and development, as is breastfeeding for an extended period of time.  Experience shows that non-breastfed babies, children, and adults of all ages benefit from colostrum supplementation.

Bovine (cow) colostrum has been shown to help with gut dysbiosis and minimize the symptoms of leaky gut, which is characterized by abnormal intestinal permeability. Overall, bovine colostrum may benefit brain health, as well as immune functions and metabolism. This results from the 100+ bioactive substances in colostrum, which can be categorized into nutritional factors, immune factors, and growth factors.

Nutritional factors refer to fats, carbohydrates, and protein, along with the diverse range of vitamins and minerals. The immune factors refer to numerous antibodies and immunoglobulins designed to support the immune system. Growth factors stimulate cell growth and repair, thereby restoring intestinal permeability to acceptable levels. Growth factors can positively affect nearly every type of tissue in the human body, thus making bovine colostrum an ideal foundational nutritional supplement.


Probiotics generally refer to the good bacteria the populate the gut. Probiotic-rich foods and supplements may help to maintain your gut bacteria, keeping the population of good bacteria at a sufficient level to prevent dysbiosis.

Probiotic-rich foods usually comprise fermented foods, including:

  • Yogurt
  • Kefir
  • Kimchi
  • Kombucha
  • Sauerkraut

In lieu of probiotic foods, you might consider taking a probiotic supplement.


Whereas probiotics repopulate gut bacteria, prebiotics act to feed the existing bacteria in your gut, helping them to grow and multiply. Prebiotics generally consist of plant-based foods high in dietary fiber. Dietary fiber cannot be digested by the human stomach, which is important. This ensures that the fiber can withstand the harsh acids of the stomach and pass into the intestines, where the majority of the gut bacteria reside. High fiber foods, including kale, broccoli, and other cruciferous vegetables, may offer prebiotic benefits.

Maintaining a healthy gut may help to support your mental and emotional health. Along with professional help, consider taking a bovine colostrum supplement from Sovereign Laboratories to help maintain the gut-brain axis.

This article was brought to you by Sovereign Laboratories, a world leader in the development of liposomal delivery to maximize the bioavailability of our dietary supplements





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bovine colostrum is full of vitamins and minerals that may support your immune system and sustain your overall health. Liposomal Colostrum contains several bioactive compounds that may contribute to a stronger immune system. Just some of these compounds include:

  • Immunoglobulins – These proteins act as antibodies that bind to pathogens and prevent them from colonizing.
  • Lactoferrin – Lactoferrin is a protein that binds to iron and possesses specific antibacterial properties.
  • Lysozyme – Lysozyme is an antibacterial enzyme that works by breaking down the cell walls of bacteria.